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WHO advises against artificial sweeteners for weight control and disease

The World Health Organization (WHO) on Monday released guidance advising against the use of non-sugar sweeteners (NSS) to control weight or manage noncommunicable diseases, citing a lack of evidence that these products have any long-term benefits.

The WHO also noted NSS use may be linked to Type 2 diabetes, cardiovascular diseases and mortality in adults. A study was released earlier this year that found a possible link between the popular zero-sugar sweetener erythritol and strokes, heart attacks, blood clots and death.

“Replacing free sugars with NSS does not help with weight control in the long term. People need to consider other ways to reduce free sugars intake, such as consuming food with naturally occurring sugars, like fruit, or unsweetened food and beverages,” said Francesco Branca, WHO director for nutrition and food safety, in a statement.

Branca noted that non-sugar sweeteners lack nutritional value and recommended people reduce the sweetness of their diets overall. Non-sugar sweeteners that are used in personal care products like toothpaste, skin cream and medications are exempted from this guidance.

This WHO recommendation includes all synthetic or natural sweeteners that aren’t classified as sugars in manufactured foods and applies to all individuals, aside from those with preexisting diabetes.


The organization listed acesulfame K, aspartame, advantame, cyclamates, neotame, saccharin, sucralose, stevia and stevia derivatives as common non-sugar sweeteners it now recommends against.

In a statement provided to The Hill, the International Sweeteners Association (ISA) pushed back against the WHO’s new guidance.

“Low/no calorie sweeteners are one of the most thoroughly researched ingredients in the world and continue to be a helpful tool to manage obesity, diabetes and dental diseases,” the ISA said. “There has been an overwhelming amount of scientific literature supporting low/no calorie sweeteners’ utility for weight management, including the WHO-commissioned systematic review itself.”